Apparently, I have not been here since 2008. My brother had been having a clean test for all of this time. Blood in his urine has returned and it is assumed that the BC has come back. He went back into the hopsital Monday to have it taken care of. But it seems he has anemia and has lost weight that he has not been able to regain, 10 pounds. Is it possible to go from superficial to late stages, so quickly? My brother does not live near by and we get minimal information. He will be 49 at the end of this month. Was a heavy smoker up until about 5 years ago. Does alcohol have an impact on the return of BC?